Pray for Grant

May 23, 2011

Posted by Melanie McTaggart on Monday, May 23, 2011

I know so many of you reading this are praying for Grant and are anxious for answers. We still have not received any word on how much, if any, Philadelphia Chromosome (PH+) is in his body. I hope we get some results today, but it is more likely tomorrow.

David and I took Grant in for counts after attending my nephew's 2nd birthday party on Saturday. Amazingly enough, his counts looked great. All his blood counts had come up significantly overnight. (Blood counts are white cells, red blood cells, platelets and ability to fight infection – aka - ANC) Since his ability to fight infection was back up, we have decided to let him do things that we normally shy away from because of germs. We figure, if he does have to have a bone marrow transplant, we want him to really enjoy life now, while he is "healthy." So yesterday, we took him breakfast and then to the museum and even watched an IMAX video. Claire and Grant had a wonderful time.

This morning, after dropping Claire off at school, we took Grant back in for counts. Again, the counts have increased. I don't want to put too much stock in it, but typically when you are relapsing, your counts go down, not up. If anything, these good counts are allowing us some time to get him out of the house and are keeping David and me sane. We are going to take the kids to see an Astros game tonight and Grant can’t wait. He told me to get his baseball shirt ready.

We spoke with Dr. Dreyer and she said we just have to wait for these other results to come back before we can make any moves. She said that it would be okay for us to go ahead and get Claire, David and I tested to see if we were a bone marrow match for him, but she really wants to see what level his Philadelphia chromosome is at before talking about it seriously. She has spoken with a few other doctors around the country and none of them have really seen this before (low cancer detection and increasing counts.) She told us a little more about the tests that were run on Friday and that the cells they were looking at really are leukemia cells. It is VERY unlikely that this is a "false positive." She also said that she spoke with one of the doctors who did the study on PH + ALL kids and one of his patients did this sort of thing that Grant is doing. She said they switched that kid to a new drug to replace the Gleevec medication he was on, and that kid went right back into remission and to date is doing fine. I hope something like this would work for Grant too.

I think our next step, besides getting these results back, is to test Grant for a PH+ gene mutation. Gleevec, the drug he is currently on, does not kill these new gene mutations. However, the newer drug, Disatinib, does. There are two gene mutations that even Disatinib can't get rid of. If Grant had one of those, then his only option would be the bone marrow transplant.

I know many of you want to know how Grant "is." He is FINE. If you saw him, you would never know something was wrong. He and his sister are playing and laughing and cutting up - just like they should be. If you are wondering how David and I are, well, we are fine too. We are hanging in there. We have forced smiles on our faces, but we are okay. We have each other and for us, that is all we need. He is my rock and I am his.

David and I are so grateful to all of you who are praying for Grant and our family. I truly believe in the power of prayer and in God's miracles. Please keep them coming.

So, that is all I have for now. I promise, as soon as I know more, I will update this.

 



 

About Me


Melanie McTaggart I am the proud mom and Claire and Grant. I am so blessed to have them in my life!

May 23, 2011

Posted by Melanie McTaggart on Monday, May 23, 2011

I know so many of you reading this are praying for Grant and are anxious for answers. We still have not received any word on how much, if any, Philadelphia Chromosome (PH+) is in his body. I hope we get some results today, but it is more likely tomorrow.

David and I took Grant in for counts after attending my nephew's 2nd birthday party on Saturday. Amazingly enough, his counts looked great. All his blood counts had come up significantly overnight. (Blood counts are white cells, red blood cells, platelets and ability to fight infection – aka - ANC) Since his ability to fight infection was back up, we have decided to let him do things that we normally shy away from because of germs. We figure, if he does have to have a bone marrow transplant, we want him to really enjoy life now, while he is "healthy." So yesterday, we took him breakfast and then to the museum and even watched an IMAX video. Claire and Grant had a wonderful time.

This morning, after dropping Claire off at school, we took Grant back in for counts. Again, the counts have increased. I don't want to put too much stock in it, but typically when you are relapsing, your counts go down, not up. If anything, these good counts are allowing us some time to get him out of the house and are keeping David and me sane. We are going to take the kids to see an Astros game tonight and Grant can’t wait. He told me to get his baseball shirt ready.

We spoke with Dr. Dreyer and she said we just have to wait for these other results to come back before we can make any moves. She said that it would be okay for us to go ahead and get Claire, David and I tested to see if we were a bone marrow match for him, but she really wants to see what level his Philadelphia chromosome is at before talking about it seriously. She has spoken with a few other doctors around the country and none of them have really seen this before (low cancer detection and increasing counts.) She told us a little more about the tests that were run on Friday and that the cells they were looking at really are leukemia cells. It is VERY unlikely that this is a "false positive." She also said that she spoke with one of the doctors who did the study on PH + ALL kids and one of his patients did this sort of thing that Grant is doing. She said they switched that kid to a new drug to replace the Gleevec medication he was on, and that kid went right back into remission and to date is doing fine. I hope something like this would work for Grant too.

I think our next step, besides getting these results back, is to test Grant for a PH+ gene mutation. Gleevec, the drug he is currently on, does not kill these new gene mutations. However, the newer drug, Disatinib, does. There are two gene mutations that even Disatinib can't get rid of. If Grant had one of those, then his only option would be the bone marrow transplant.

I know many of you want to know how Grant "is." He is FINE. If you saw him, you would never know something was wrong. He and his sister are playing and laughing and cutting up - just like they should be. If you are wondering how David and I are, well, we are fine too. We are hanging in there. We have forced smiles on our faces, but we are okay. We have each other and for us, that is all we need. He is my rock and I am his.

David and I are so grateful to all of you who are praying for Grant and our family. I truly believe in the power of prayer and in God's miracles. Please keep them coming.

So, that is all I have for now. I promise, as soon as I know more, I will update this.