Pray for Grant

Thursday, March 25 - 3:04 p.m.

Posted by Melanie McTaggart on Thursday, March 25, 2010

So far so good. Almost too good.
Grant completed his Methotrexate at 10:30 a.m. today. This bag of chemo runs for 24 straight hours. For some reason, still unknown, his bag was not empty at 24 hours, so they increased his rate of infusion and then shut it off at hour 25. With that said, they never had to adjust his dose downwards this time. His electrolytes stayed stable the entire time and he never got puffy looking. In fact, his methotrexate levels were actually LOWER than they would have preferred. They would have liked him to have a methotrexate level of about 60 and he ended up at 48.9. Just to refresh your minds, the first time Grant received this drug, he ended up overdosed and had a level at 148. The second time he got it, they gave him a 25% less dose and at hour one, he was already at level 85, so they had to reduce it again. This time though he handled it just fine and will most likely start with a full dose the next time he gets it - in about two months.

We have to wait until he clears all the methrotrexate out of his system and post hydrate to protect his kidneys for 72 hours. So, it all goes as planned, we should be out of here Saturday morning. At 3:00 a.m. they will give him the first of 5 doses of a rescue drug that helps counterbalance the bad side effects of methotrexate. It helps keep his mouth sores to a minimum and helps to get the drug out of his system. Last time he got methotrexate, he had cleared it before the 1st dose of this rescue drug. I hope he does the same this time.

We went to physical therapy today. It has been a while since he has been able to go due to his counts and hospital admissions with fevers so I was thrilled that he could go. He did really well. In fact, the physical therapist told me that she does not think he has ataxia (shaking caused by damage to the brain) anymore. That he does have some front leg weakness still and has foot drop  - more severe on his left foot. That is from the drug Vincristine that he will continue to get until he is through with treatment in January 2012. So, I have a feeling we will be dealing with this for a while longer. However, we did put him back in his leg (foot rather) braces and he walked much better. I guess the braces make it harder for him to drop the front part of his foot when walking and makes it easier for him to take a more natural full heal-to-toe step. So the people who made the braces are supposed to come out tomorrow and check them and make some adjustments to them so they will be more comfortable for him now that he has put on some weight and muscles!!

Well, that is it for now. Grant is sound asleep - taking his afternoon nap. I'll update more when I know more!



 

About Me


Melanie McTaggart I am the proud mom and Claire and Grant. I am so blessed to have them in my life!

Thursday, March 25 - 3:04 p.m.

Posted by Melanie McTaggart on Thursday, March 25, 2010

So far so good. Almost too good.
Grant completed his Methotrexate at 10:30 a.m. today. This bag of chemo runs for 24 straight hours. For some reason, still unknown, his bag was not empty at 24 hours, so they increased his rate of infusion and then shut it off at hour 25. With that said, they never had to adjust his dose downwards this time. His electrolytes stayed stable the entire time and he never got puffy looking. In fact, his methotrexate levels were actually LOWER than they would have preferred. They would have liked him to have a methotrexate level of about 60 and he ended up at 48.9. Just to refresh your minds, the first time Grant received this drug, he ended up overdosed and had a level at 148. The second time he got it, they gave him a 25% less dose and at hour one, he was already at level 85, so they had to reduce it again. This time though he handled it just fine and will most likely start with a full dose the next time he gets it - in about two months.

We have to wait until he clears all the methrotrexate out of his system and post hydrate to protect his kidneys for 72 hours. So, it all goes as planned, we should be out of here Saturday morning. At 3:00 a.m. they will give him the first of 5 doses of a rescue drug that helps counterbalance the bad side effects of methotrexate. It helps keep his mouth sores to a minimum and helps to get the drug out of his system. Last time he got methotrexate, he had cleared it before the 1st dose of this rescue drug. I hope he does the same this time.

We went to physical therapy today. It has been a while since he has been able to go due to his counts and hospital admissions with fevers so I was thrilled that he could go. He did really well. In fact, the physical therapist told me that she does not think he has ataxia (shaking caused by damage to the brain) anymore. That he does have some front leg weakness still and has foot drop  - more severe on his left foot. That is from the drug Vincristine that he will continue to get until he is through with treatment in January 2012. So, I have a feeling we will be dealing with this for a while longer. However, we did put him back in his leg (foot rather) braces and he walked much better. I guess the braces make it harder for him to drop the front part of his foot when walking and makes it easier for him to take a more natural full heal-to-toe step. So the people who made the braces are supposed to come out tomorrow and check them and make some adjustments to them so they will be more comfortable for him now that he has put on some weight and muscles!!

Well, that is it for now. Grant is sound asleep - taking his afternoon nap. I'll update more when I know more!